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Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice

Gene transfer has proven to be an effective neurobiological tool in a number of neurodegenerative diseases, but it is not known if it can correct a sleep disorder. Narcolepsy is a neurodegenerative sleep disorder linked to the loss of neurons containing the neuropeptide orexin, also known as hypocre...

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Detalhes bibliográficos
Main Authors: Liu, Meng, Thankachan, Stephen, Kaur, Satvinder, Begum, Suraiya, Blanco-Centurion, Carlos, Sakurai, Takeshi, Yanagisawa, Masashi, Neve, Rachael, Shiromani, Priyattam J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615183/
https://ncbi.nlm.nih.gov/pubmed/18973565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2008.06446.x
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