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Sphingosine phosphate lyase regulates myogenic differentiation via S1P receptor-mediated effects on myogenic microRNA expression

S1P lyase (SPL) catalyzes the irreversible degradation of sphingosine-1-phosphate (S1P), a bioactive lipid whose signaling activities regulate muscle differentiation, homeostasis, and satellite cell (SC) activation. By regulating S1P levels, SPL also controls SC recruitment and muscle regeneration,...

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Bibliographic Details
Main Authors: de la Garza-Rodea, Anabel S., Baldwin, Dianna M., Oskouian, Babak, Place, Robert F., Bandhuvula, Padmavathi, Kumar, Ashok, Saba, Julie D.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868843/
https://ncbi.nlm.nih.gov/pubmed/24158395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-233155
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