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Sphingosine 1-phosphate lyase enzyme assay using a BODIPY-labeled substrate

Sphingosine 1-phosphate lyase (SPL) is responsible for the irreversible catabolism of sphingosine 1-phosphate, which signals through five membrane receptors to mediate cell stress responses, angiogenesis, and lymphocyte trafficking. The standard assay for SPL activity utilizes a radioactive dihydros...

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Detalhes bibliográficos
Main Authors: Bandhuvula, Padmavathi, Li, Zaiguo, Bittman, Robert, Saba, Julie D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790368/
https://ncbi.nlm.nih.gov/pubmed/19250638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.01.106
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