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Lyase to live by: Sphingosine phosphate lyase as a therapeutic target

BACKGROUND: Sphingosine 1-phosphate (S1P) is a bioactive lipid that regulates cell proliferation, survival and migration and plays an essential role in angiogenesis and lymphocyte trafficking. S1P levels in the circulation and tissues are tightly regulated for proper cell functioning, and dysregulat...

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Detalhes bibliográficos
Main Authors: Kumar, Ashok, Saba, Julie D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774446/
https://ncbi.nlm.nih.gov/pubmed/19534571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728220903039722
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