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Lyase to live by: Sphingosine phosphate lyase as a therapeutic target
BACKGROUND: Sphingosine 1-phosphate (S1P) is a bioactive lipid that regulates cell proliferation, survival and migration and plays an essential role in angiogenesis and lymphocyte trafficking. S1P levels in the circulation and tissues are tightly regulated for proper cell functioning, and dysregulat...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774446/ https://ncbi.nlm.nih.gov/pubmed/19534571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728220903039722 |
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