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Lyase to live by: Sphingosine phosphate lyase as a therapeutic target

BACKGROUND: Sphingosine 1-phosphate (S1P) is a bioactive lipid that regulates cell proliferation, survival and migration and plays an essential role in angiogenesis and lymphocyte trafficking. S1P levels in the circulation and tissues are tightly regulated for proper cell functioning, and dysregulat...

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Bibliografski detalji
Glavni autori: Kumar, Ashok, Saba, Julie D.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774446/
https://ncbi.nlm.nih.gov/pubmed/19534571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728220903039722
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