Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid involved in immunity, inflammation, angiogenesis, and cancer. S1P lyase (SPL) is the essential enzyme responsible for S1P degradation. SPL augments apoptosis and is down-regulated in cancer. SPL generates a S1P chemical gradient that promotes...

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Main Authors: Borowsky, Alexander D., Bandhuvula, Padmavathi, Kumar, Ashok, Yoshinaga, Yuko, Nefedov, Mikhail, Fong, Loren G., Zhang, Meng, Baridon, Brian, Dillard, Lisa, de Jong, Pieter, Young, Stephen G., West, David B., Saba, Julie D.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2012
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413231/
https://ncbi.nlm.nih.gov/pubmed/22781001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M028084
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