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Biochemical and Functional Characterization of the Klotho-VS Polymorphism Implicated in Aging and Disease Risk

Klotho (KL) is an age-regulating protein named after the Greek goddess who spins the thread of life. Mice deficient in KL are normal throughout development, but rapidly degenerate and display a variety of aging-associated abnormalities that eventually lead to decreased life expectancy. While multipl...

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Detalhes bibliográficos
Main Authors: Tucker Zhou, Tracey B., King, Gwendalyn D., Chen, CiDi, Abraham, Carmela R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868745/
https://ncbi.nlm.nih.gov/pubmed/24217253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.490052
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