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Identification of novel small molecules that elevate Klotho expression
The absence of Klotho (KL) from mice causes the development of disorders associated with human aging and decreased longevity, whereas increased expression prolongs lifespan. With age, KL protein levels decrease, and keeping levels consistent may promote healthier aging and be disease-modifying. Usin...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3677209/ https://ncbi.nlm.nih.gov/pubmed/21939436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101909 |
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