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Identification of novel small molecules that elevate Klotho expression

The absence of Klotho (KL) from mice causes the development of disorders associated with human aging and decreased longevity, whereas increased expression prolongs lifespan. With age, KL protein levels decrease, and keeping levels consistent may promote healthier aging and be disease-modifying. Usin...

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Detalhes bibliográficos
Main Authors: King, Gwendalyn D., Chen, CiDi, Huang, Mickey M., Zeldich, Ella, Brazee, Patricia L., Schuman, Eli R., Robin, Maxime, Cuny, Gregory D., Glicksman, Marcie A., Abraham, Carmela R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677209/
https://ncbi.nlm.nih.gov/pubmed/21939436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101909
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