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Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-β precursor protein dimerization

The amyloid β precursor protein (APP) is a single-pass transmembrane glycoprotein that is ubiquitously expressed in many cell types, including neurons. Amyloidogenic processing of APP by β- and γ-secretases leads to the production of amyloid-β (Aβ) peptides that can oligomerize and aggregate into am...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: So, Pauline PL, Zeldich, Ella, Seyb, Kathleen I, Huang, Mickey M, Concannon, John B, King, Gwendalyn D, Chen, Ci-Di, Cuny, Gregory D, Glicksman, Marcie A, Abraham, Carmela R
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: e-Century Publishing Corporation 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560454/
https://ncbi.nlm.nih.gov/pubmed/22822474
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