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MicroRNA-339 and microRNA-556 regulate Klotho expression in vitro

Klotho is an anti-aging protein with direct effects on life-span in mice. Klotho functions to regulate pathways classically associated with longevity including insulin/IGF1 and Wnt signaling. Decreased Klotho protein expression is observed throughout the body during the normal aging process. While i...

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Détails bibliographiques
Auteurs principaux: Mehi, Stephen J., Maltare, Astha, Abraham, Carmela R., King, Gwendalyn D.
Format: Artigo
Langue:Inglês
Publié: Springer Netherlands 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889880/
https://ncbi.nlm.nih.gov/pubmed/23818104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-013-9555-6
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