microRNA-200c regulates KLOTHO expression in human kidney cells under oxidative stress

KLOTHO deficiency is associated with the progression of kidney dysfunction, whereas its overexpression exerts renoprotective effects. Oxidative stress suppresses KLOTHO expression in renal epithelial cells but upregulates microRNA-200c (miR-200c) in human umbilical vein endothelial cells. In this st...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Morii, Kenichi, Yamasaki, Satoshi, Doi, Shigehiro, Irifuku, Taisuke, Sasaki, Kensuke, Doi, Toshiki, Nakashima, Ayumu, Arihiro, Koji, Masaki, Takao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568409/
https://ncbi.nlm.nih.gov/pubmed/31199854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218468
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