microRNA-200c regulates KLOTHO expression in human kidney cells under oxidative stress

KLOTHO deficiency is associated with the progression of kidney dysfunction, whereas its overexpression exerts renoprotective effects. Oxidative stress suppresses KLOTHO expression in renal epithelial cells but upregulates microRNA-200c (miR-200c) in human umbilical vein endothelial cells. In this st...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Morii, Kenichi, Yamasaki, Satoshi, Doi, Shigehiro, Irifuku, Taisuke, Sasaki, Kensuke, Doi, Toshiki, Nakashima, Ayumu, Arihiro, Koji, Masaki, Takao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568409/
https://ncbi.nlm.nih.gov/pubmed/31199854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218468
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