microRNA-200c regulates KLOTHO expression in human kidney cells under oxidative stress

KLOTHO deficiency is associated with the progression of kidney dysfunction, whereas its overexpression exerts renoprotective effects. Oxidative stress suppresses KLOTHO expression in renal epithelial cells but upregulates microRNA-200c (miR-200c) in human umbilical vein endothelial cells. In this st...

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Vydáno v:PLoS One
Hlavní autoři: Morii, Kenichi, Yamasaki, Satoshi, Doi, Shigehiro, Irifuku, Taisuke, Sasaki, Kensuke, Doi, Toshiki, Nakashima, Ayumu, Arihiro, Koji, Masaki, Takao
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568409/
https://ncbi.nlm.nih.gov/pubmed/31199854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218468
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