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Expression of klotho mRNA and protein in rat brain parenchyma from early postnatal development into adulthood

Without the age-regulating protein klotho, mouse lifespan is shortened and the rapid onset of age-related disorders occurs. Conversely, overexpression of klotho extends mouse lifespan. Klotho is most abundant in kidney and expressed in a limited number of other organs, including the brain, where klo...

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Detalhes bibliográficos
Main Authors: Clinton, Sarah M., Glover, Matthew E., Maltare, Astha, Laszczyk, Ann M., Mehi, Stephen J., Simmons, Rebecca K., King, Gwendalyn D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756829/
https://ncbi.nlm.nih.gov/pubmed/23838326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2013.06.044
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