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Cofactor Molecules Induce Structural Transformation During Infectious Prion Formation
The spread of misfolded proteins has been implicated in a wide variety of neurodegenerative diseases. Prions associated with spongiform encephalopathy are currently the only misfolded proteins in which high specific biological infectivity can be produced in vitro. Using a system that generates infec...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3863764/ https://ncbi.nlm.nih.gov/pubmed/24120764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.08.025 |
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