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Computational Design of an Unnatural Amino Acid Dependent Metalloprotein with Atomic Level Accuracy
Genetically encoded unnatural amino acids could facilitate the design of proteins and enzymes of novel function, but correctly specifying sites of incorporation, and the identities and orientations of surrounding residues represents a formidable challenge. Computational design methods have been used...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3863684/ https://ncbi.nlm.nih.gov/pubmed/23924187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja403503m |
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