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Atomic accuracy in predicting and designing non-canonical RNA structure

We present a Rosetta full-atom framework for predicting and designing the non-canonical motifs that define RNA tertiary structure, called FARFAR (Fragment Assembly of RNA with Full Atom Refinement). For a test set of thirty-two 6-to-20-nucleotide motifs, the method recapitulated 50% of the experimen...

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Detalhes bibliográficos
Main Authors: Das, Rhiju, Karanicolas, John, Baker, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854559/
https://ncbi.nlm.nih.gov/pubmed/20190761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1433
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