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Automated de novo prediction of native-like RNA tertiary structures

RNA tertiary structure prediction has been based almost entirely on base-pairing constraints derived from phylogenetic covariation analysis. We describe here a complementary approach, inspired by the Rosetta low-resolution protein structure prediction method, that seeks the lowest energy tertiary st...

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Bibliografiske detaljer
Main Authors: Das, Rhiju, Baker, David
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955458/
https://ncbi.nlm.nih.gov/pubmed/17726102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703836104
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