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Prospects for de novo phasing with de novo protein models

The prospect of phasing diffraction data sets ‘de novo’ for proteins with previously unseen folds is appealing but largely untested. In a first systematic exploration of phasing with Rosetta de novo models, it is shown that all-atom refinement of coarse-grained models significantly improves both the...

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Detalhes bibliográficos
Main Authors: Das, Rhiju, Baker, David
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631639/
https://ncbi.nlm.nih.gov/pubmed/19171972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444908020039
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