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Prospects for de novo phasing with de novo protein models

The prospect of phasing diffraction data sets ‘de novo’ for proteins with previously unseen folds is appealing but largely untested. In a first systematic exploration of phasing with Rosetta de novo models, it is shown that all-atom refinement of coarse-grained models significantly improves both the...

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Autori principali: Das, Rhiju, Baker, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631639/
https://ncbi.nlm.nih.gov/pubmed/19171972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444908020039
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