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Prospects for de novo phasing with de novo protein models

The prospect of phasing diffraction data sets ‘de novo’ for proteins with previously unseen folds is appealing but largely untested. In a first systematic exploration of phasing with Rosetta de novo models, it is shown that all-atom refinement of coarse-grained models significantly improves both the...

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Autors principals: Das, Rhiju, Baker, David
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631639/
https://ncbi.nlm.nih.gov/pubmed/19171972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444908020039
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