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Cyclic oligomer design with de novo αβ‐proteins

We have previously shown that monomeric globular αβ‐proteins can be designed de novo with considerable control over topology, size, and shape. In this paper, we investigate the design of cyclic homo‐oligomers from these starting points. We experimented with both keeping the original monomer backbone...

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Bibliografiske detaljer
Udgivet i:Protein Sci
Main Authors: Lin, Yu‐Ru, Koga, Nobuyasu, Vorobiev, Sergey M., Baker, David
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654858/
https://ncbi.nlm.nih.gov/pubmed/28801928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3270
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