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Cyclic oligomer design with de novo αβ‐proteins

We have previously shown that monomeric globular αβ‐proteins can be designed de novo with considerable control over topology, size, and shape. In this paper, we investigate the design of cyclic homo‐oligomers from these starting points. We experimented with both keeping the original monomer backbone...

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Bibliografiska uppgifter
I publikationen:Protein Sci
Huvudupphovsmän: Lin, Yu‐Ru, Koga, Nobuyasu, Vorobiev, Sergey M., Baker, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654858/
https://ncbi.nlm.nih.gov/pubmed/28801928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3270
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