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Cyclic oligomer design with de novo αβ‐proteins

We have previously shown that monomeric globular αβ‐proteins can be designed de novo with considerable control over topology, size, and shape. In this paper, we investigate the design of cyclic homo‐oligomers from these starting points. We experimented with both keeping the original monomer backbone...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Protein Sci
Egile Nagusiak: Lin, Yu‐Ru, Koga, Nobuyasu, Vorobiev, Sergey M., Baker, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654858/
https://ncbi.nlm.nih.gov/pubmed/28801928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3270
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