Robust folding of a de novo designed ideal protein even with most of the core mutated to valine

Protein design provides a stringent test for our understanding of protein folding. We previously described principles for designing ideal protein structures stabilized by consistent local and nonlocal interactions, based on a set of rules relating local backbone structures to tertiary packing motifs...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Koga, Rie, Yamamoto, Mami, Kosugi, Takahiro, Kobayashi, Naohiro, Sugiki, Toshihiko, Fujiwara, Toshimichi, Koga, Nobuyasu
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739874/
https://ncbi.nlm.nih.gov/pubmed/33229587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2002120117
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki