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Folding-based molecular simulations reveal mechanisms of the rotary motor F(1)–ATPase

Biomolecular machines fulfill their function through large conformational changes that typically occur on the millisecond time scale or longer. Conventional atomistic simulations can only reach microseconds at the moment. Here, extending the minimalist model developed for protein folding, we propose...

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Detalhes bibliográficos
Main Authors: Koga, Nobuyasu, Takada, Shoji
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459361/
https://ncbi.nlm.nih.gov/pubmed/16567655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509642103
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