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How protein thermodynamics and folding mechanisms are altered by the chaperonin cage: Molecular simulations
How the Escherichia coli GroEL/ES chaperonin assists folding of a substrate protein remains to be uncovered. Recently, it was suggested that confinement into the chaperonin cage itself can significantly accelerate folding of a substrate. Performing comprehensive molecular simulations of eight protei...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC208763/ https://ncbi.nlm.nih.gov/pubmed/12947041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1831920100 |
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