How protein thermodynamics and folding mechanisms are altered by the chaperonin cage: Molecular simulations
How the Escherichia coli GroEL/ES chaperonin assists folding of a substrate protein remains to be uncovered. Recently, it was suggested that confinement into the chaperonin cage itself can significantly accelerate folding of a substrate. Performing comprehensive molecular simulations of eight protei...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2003
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208763/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12947041/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1831920100 |
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