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Folding-based molecular simulations reveal mechanisms of the rotary motor F(1)–ATPase
Biomolecular machines fulfill their function through large conformational changes that typically occur on the millisecond time scale or longer. Conventional atomistic simulations can only reach microseconds at the moment. Here, extending the minimalist model developed for protein folding, we propose...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1459361/ https://ncbi.nlm.nih.gov/pubmed/16567655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509642103 |
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