Control over overall shape and size in de novo designed proteins

We recently described general principles for designing ideal protein structures stabilized by completely consistent local and nonlocal interactions. The principles relate secondary structure patterns to tertiary packing motifs and enable design of different protein topologies. To achieve fine contro...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Lin, Yu-Ru, Koga, Nobuyasu, Tatsumi-Koga, Rie, Liu, Gaohua, Clouser, Amanda F., Montelione, Gaetano T., Baker, David
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
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PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603489/
https://ncbi.nlm.nih.gov/pubmed/26396255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509508112
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