Control over overall shape and size in de novo designed proteins

We recently described general principles for designing ideal protein structures stabilized by completely consistent local and nonlocal interactions. The principles relate secondary structure patterns to tertiary packing motifs and enable design of different protein topologies. To achieve fine contro...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Lin, Yu-Ru, Koga, Nobuyasu, Tatsumi-Koga, Rie, Liu, Gaohua, Clouser, Amanda F., Montelione, Gaetano T., Baker, David
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603489/
https://ncbi.nlm.nih.gov/pubmed/26396255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509508112
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