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An enumerative stepwise ansatz enables atomic-accuracy RNA loop modeling
Atomic-accuracy structure prediction of macromolecules should be achievable by optimizing a physically realistic energy function but is presently precluded by incomplete sampling of a biopolymer’s many degrees of freedom. We present herein a working hypothesis, called the “stepwise ansatz,” for recu...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251086/ https://ncbi.nlm.nih.gov/pubmed/22143768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106516108 |
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