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An enumerative stepwise ansatz enables atomic-accuracy RNA loop modeling

Atomic-accuracy structure prediction of macromolecules should be achievable by optimizing a physically realistic energy function but is presently precluded by incomplete sampling of a biopolymer’s many degrees of freedom. We present herein a working hypothesis, called the “stepwise ansatz,” for recu...

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Autori principali: Sripakdeevong, Parin, Kladwang, Wipapat, Das, Rhiju
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251086/
https://ncbi.nlm.nih.gov/pubmed/22143768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106516108
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