A critical role for Lyn kinase in strengthening endothelial integrity and barrier function

The Src family kinases (SFKs) c-Src and Yes mediate vascular leakage in response to various stimuli including lipopolysaccharide (LPS) and vascular endothelial growth factor (VEGF). Here, we define an opposing function of another SFK, Lyn, which in contrast to other SFKs, strengthens endothelial jun...

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Bibliografiska uppgifter
Huvudupphovsmän: Han, Jingyan, Zhang, Guoying, Welch, Emily J., Liang, Ying, Fu, Jian, Vogel, Stephen M., Lowell, Clifford A., Du, Xiaoping, Cheresh, David A., Malik, Asrar B., Li, Zhenyu
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2013
Ämnen:
Vascular Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862279/
https://ncbi.nlm.nih.gov/pubmed/24108461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-491423
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