An Important Role of the Src Family Kinase Lyn in Stimulating Platelet Granule Secretion

The Src family kinases (SFKs) have been proposed to play stimulatory and inhibitory roles in platelet activation. The mechanisms for these apparently contradictory roles are unclear. Here we show that SFK, mainly Lyn, is important in stimulating a common signaling pathway leading to secretion of pla...

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Autors principals: Li, Zhenyu, Zhang, Guoying, Liu, Junling, Stojanovic, Aleksandra, Ruan, Changgeng, Lowell, Clifford A., Du, Xiaoping
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857081/
https://ncbi.nlm.nih.gov/pubmed/20189992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.098756
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