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An Important Role of the Src Family Kinase Lyn in Stimulating Platelet Granule Secretion

The Src family kinases (SFKs) have been proposed to play stimulatory and inhibitory roles in platelet activation. The mechanisms for these apparently contradictory roles are unclear. Here we show that SFK, mainly Lyn, is important in stimulating a common signaling pathway leading to secretion of pla...

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Detalhes bibliográficos
Main Authors: Li, Zhenyu, Zhang, Guoying, Liu, Junling, Stojanovic, Aleksandra, Ruan, Changgeng, Lowell, Clifford A., Du, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857081/
https://ncbi.nlm.nih.gov/pubmed/20189992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.098756
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