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A critical role for Lyn kinase in strengthening endothelial integrity and barrier function

The Src family kinases (SFKs) c-Src and Yes mediate vascular leakage in response to various stimuli including lipopolysaccharide (LPS) and vascular endothelial growth factor (VEGF). Here, we define an opposing function of another SFK, Lyn, which in contrast to other SFKs, strengthens endothelial jun...

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Bibliografiske detaljer
Main Authors: Han, Jingyan, Zhang, Guoying, Welch, Emily J., Liang, Ying, Fu, Jian, Vogel, Stephen M., Lowell, Clifford A., Du, Xiaoping, Cheresh, David A., Malik, Asrar B., Li, Zhenyu
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862279/
https://ncbi.nlm.nih.gov/pubmed/24108461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-491423
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