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Critical role of Cdc42 in mediating endothelial barrier protection in vivo

Activation of the Rho GTPase Cdc42 has been shown in endothelial cell monolayers to prevent disassembly of interendothelial junctions and the increase in endothelial permeability. Here, we addressed the in vivo role of Cdc42 activity in mediating endothelial barrier protection in lungs by generating...

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Détails bibliographiques
Auteurs principaux: Ramchandran, Ramaswamy, Mehta, Dolly, Vogel, Stephen M., Mirza, Muhammad K., Kouklis, Panos, Malik, Asrar B.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2008
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519844/
https://ncbi.nlm.nih.gov/pubmed/18515405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90241.2008
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