A critical role for Lyn kinase in strengthening endothelial integrity and barrier function

The Src family kinases (SFKs) c-Src and Yes mediate vascular leakage in response to various stimuli including lipopolysaccharide (LPS) and vascular endothelial growth factor (VEGF). Here, we define an opposing function of another SFK, Lyn, which in contrast to other SFKs, strengthens endothelial jun...

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Autori principali: Han, Jingyan, Zhang, Guoying, Welch, Emily J., Liang, Ying, Fu, Jian, Vogel, Stephen M., Lowell, Clifford A., Du, Xiaoping, Cheresh, David A., Malik, Asrar B., Li, Zhenyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2013
Soggetti:
Vascular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862279/
https://ncbi.nlm.nih.gov/pubmed/24108461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-491423
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