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Insulin receptor isoform switching in intestinal stem cells, progenitors, differentiated lineages and tumors: evidence that IR-B limits proliferation

Despite evidence for the impact of insulin on intestinal epithelial physiology and pathophysiology, the expression patterns, roles, and regulation of insulin receptor (IR) and IR isoforms in the intestinal epithelium are not well characterized. IR-A is thought to mediate the proliferative effects of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Andres, Sarah F., Simmons, James G., Mah, Amanda T., Santoro, M. Agostina, Van Landeghem, Laurianne, Lund, P. Kay
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3860310/
https://ncbi.nlm.nih.gov/pubmed/24127567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.132985
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