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Hexokinase activity is required for recruitment of parkin to depolarized mitochondria

Autosomal recessive parkinsonism genes contribute to maintenance of mitochondrial function. Two of these, PINK1 and parkin, act in a pathway promoting autophagic removal of depolarized mitochondria. Although recruitment of parkin to mitochondria is PINK1-dependent, additional components necessary fo...

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Bibliografische gegevens
Hoofdauteurs: McCoy, Melissa K., Kaganovich, Alice, Rudenko, Iakov N., Ding, Jinhui, Cookson, Mark R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857951/
https://ncbi.nlm.nih.gov/pubmed/23962723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt407
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