Hexokinase activity is required for recruitment of parkin to depolarized mitochondria

Por McCoy, Melissa K., Kaganovich, Alice, Rudenko, Iakov N., Ding, Jinhui, Cookson, Mark R.
Publicado em 2014

The Parkinson's Disease Associated LRRK2 Exhibits Weaker In Vitro Phosphorylation of 4E-BP Compared to Autophosphorylation

Por Kumar, Azad, Greggio, Elisa, Beilina, Alexandra, Kaganovich, Alice, Chan, Diane, Taymans, Jean-Marc, Wolozin, Benjamin, Cookson, Mark R.
Publicado em 2010

The G2385R Variant of Leucine-Rich Repeat Kinase 2 Associated with Parkinson's Disease is a Partial Loss of Function Mutation

Por Rudenko, Iakov N., Kaganovich, Alice, Hauser, David N., Beylina, Aleksandra, Chia, Ruth, Ding, Jinhui, Maric, Dragan, Jaffe, Howard, Cookson, Mark R.
Publicado no Biochem J (2012)

Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7

Por Chia, Ruth, Haddock, Sara, Beilina, Alexandra, Rudenko, Iakov N, Mamais, Adamantios, Kaganovich, Alice, Li, Yan, Kumaran, Ravindran, Nalls, Michael A, Cookson, Mark R
Publicado no Nat Commun (2014)

The Parkinson Disease-associated Leucine-rich Repeat Kinase 2 (LRRK2) Is a Dimer That Undergoes Intramolecular Autophosphorylation

Por Greggio, Elisa, Zambrano, Ibardo, Kaganovich, Alice, Beilina, Alexandra, Taymans, Jean-Marc, Daniëls, Veronique, Lewis, Patrick, Jain, Shushant, Ding, Jinhui, Syed, Ali, Thomas, Kelly J., Baekelandt, Veerle, Cookson, Mark R.
Publicado em 2008

A soluble α-synuclein construct forms a dynamic tetramer

Por Wang, Wei, Perovic, Iva, Chittuluru, Johnathan, Kaganovich, Alice, Nguyen, Linh T. T., Liao, Jingling, Auclair, Jared R., Johnson, Derrick, Landeru, Anuradha, Simorellis, Alana K., Ju, Shulin, Cookson, Mark R., Asturias, Francisco J., Agar, Jeffrey N., Webb, Brian N., Kang, ChulHee, Ringe, Dagmar, Petsko, Gregory A., Pochapsky, Thomas C., Hoang, Quyen Q.
Publicado em 2011

Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue

Por Devine, Michael J., Kaganovich, Alice, Ryten, Mina, Mamais, Adamantios, Trabzuni, Daniah, Manzoni, Claudia, McGoldrick, Philip, Chan, Diane, Dillman, Allissa, Zerle, Julia, Horan, Susannah, Taanman, Jan-Willem, Hardy, John, Marti-Masso, Jose-Felix, Healey, Daniel, Schapira, Anthony H., Wolozin, Benjamin, Bandopadhyay, Rina, Cookson, Mark R., van der Brug, Marcel P., Lewis, Patrick A.
Publicado em 2011

Correction: Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue

Por Devine, Michael J., Kaganovich, Alice, Ryten, Mina, Mamais, Adamantios, Trabzuni, Daniah, Manzoni, Claudia, McGoldrick, Philip, Chan, Diane, Dillman, Allissa, Zerle, Julia, Horan, Susannah, Taanman, Jan-Willem, Hardy, John, Marti-Masso, Jose-Felix, Healy, Daniel, Schapira, Anthony H., Wolozin, Benjamin, Bandopadhyay, Rina, Cookson, Mark R., van der Brug, Marcel P., Lewis, Patrick A.
Publicado em 2012

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

Por Renton, Alan E., Majounie, Elisa, Waite, Adrian, Simón-Sánchez, Javier, Rollinson, Sara, Gibbs, J. Raphael, Schymick, Jennifer C., Laaksovirta, Hannu, van Swieten, John C., Myllykangas, Liisa, Kalimo, Hannu, Paetau, Anders, Abramzon, Yevgeniya, Remes, Anne M., Kaganovich, Alice, Scholz, Sonja W., Duckworth, Jamie, Ding, Jinhui, Harmer, Daniel W., Hernandez, Dena G., Johnson, Janel O., Mok, Kin, Ryten, Mina, Trabzuni, Danyah, Guerreiro, Rita J., Orrell, Richard W., Neal, James, Murray, Alex, Pearson, Justin, Jansen, Iris E., Sondervan, David, Seelaar, Harro, Blake, Derek, Young, Kate, Halliwell, Nicola, Callister, Janis, Toulson, Greg, Richardson, Anna, Gerhard, Alex, Snowden, Julie, Mann, David, Neary, David, Nalls, Michael A., Peuralinna, Terhi, Jansson, Lilja, Isoviita, Veli-Matti, Kaivorinne, Anna-Lotta, Hölttä-Vuori, Maarit, Ikonen, Elina, Sulkava, Raimo, Benatar, Michael, Wuu, Joanne, Chiò, Adriano, Restagno, Gabriella, Borghero, Giuseppe, Sabatelli, Mario, Heckerman, David, Rogaeva, Ekaterina, Zinman, Lorne, Rothstein, Jeffrey, Sendtner, Michael, Drepper, Carsten, Eichler, Evan E., Alkan, Can, Abdullaev, Zied, Pack, Svetlana D., Dutra, Amalia, Pak, Evgenia, Hardy, John, Singleton, Andrew, Williams, Nigel M., Heutink, Peter, Pickering-Brown, Stuart, Morris, Huw R., Tienari, Pentti J., Traynor, Bryan J.
Publicado em 2011

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

Por Beilina, Alexandria, Rudenko, Iakov N., Kaganovich, Alice, Civiero, Laura, Chau, Hien, Kalia, Suneil K., Kalia, Lorraine V., Lobbestael, Evy, Chia, Ruth, Ndukwe, Kelechi, Ding, Jinhui, Nalls, Mike A., Olszewski, Maciej, Hauser, David N., Kumaran, Ravindran, Lozano, Andres M., Baekelandt, Veerle, Greene, Lois E., Taymans, Jean-Marc, Greggio, Elisa, Cookson, Mark R., Nalls, Mike A., Plagnol, Vincent, Martinez, Maria, Hernandez, Dena G, Sharma, Manu, Sheerin, Una-Marie, Saad, Mohamad, Simón-Sánchez, Javier, Schulte, Claudia, Lesage, Suzanne, Sveinbjörnsdóttir, Sigurlaug, Arepalli, Sampath, Barker, Roger, Ben-Shlomo, Yoav, Berendse, Henk W, Berg, Daniela, Bhatia, Kailash, de Bie, Rob M A, Biffi, Alessandro, Bloem, Bas, Bochdanovits, Zoltan, Bonin, Michael, Bras, Jose M, Brockmann, Kathrin, Brooks, Janet, Burn, David J, Charlesworth, Gavin, Chen, Honglei, Chong, Sean, Clarke, Carl E, Cookson, Mark R, Cooper, J Mark, Corvol, Jean Christophe, Counsell, Carl, Damier, Philippe, Dartigues, Jean-François, Deloukas, Panos, Deuschl, Günther, Dexter, David T, van Dijk, Karin D, Dillman, Allissa, Durif, Frank, Dürr, Alexandra, Edkins, Sarah, Evans, Jonathan R, Foltynie, Thomas, Gao, Jianjun, Gardner, Michelle, Gibbs, J Raphael, Goate, Alison, Gray, Emma, Guerreiro, Rita, Gústafsson, Ómar, Harris, Clare, van Hilten, Jacobus J, Hofman, Albert, Hollenbeck, Albert, Holton, Janice, Hu, Michele, Huang, Xuemei, Huber, Heiko, Hudson, Gavin, Hunt, Sarah E, Huttenlocher, Johanna, Illig, Thomas, München, Helmholtz Zentrum, Jónsson, Pálmi V, Lambert, Jean-Charles, Langford, Cordelia, Lees, Andrew, Lichtner, Peter, München, Helmholtz Zentrum, Limousin, Patricia, Lopez, Grisel, Lorenz, Delia, McNeill, Alisdair, Moorby, Catriona, Moore, Matthew, Morris, Huw R, Morrison, Karen E, Mudanohwo, Ese, O’Sullivan, Sean S, Pearson, Justin, Perlmutter, Joel S, Pétursson, Hjörvar, Pollak, Pierre, Post, Bart, Potter, Simon, Ravina, Bernard, Revesz, Tamas, Riess, Olaf, Rivadeneira, Fernando, Rizzu, Patrizia, Ryten, Mina, Sawcer, Stephen, Schapira, Anthony, Scheffer, Hans, Shaw, Karen, Shoulson, Ira, Sidransky, Ellen, Smith, Colin, Spencer, Chris C A, Stefánsson, Hreinn, Steinberg, Stacy, Stockton, Joanna D, Strange, Amy, Talbot, Kevin, Tanner, Carlie M, Tashakkori-Ghanbaria, Avazeh, Tison, François, Trabzuni, Daniah, Traynor, Bryan J, Uitterlinden, André G, Velseboer, Daan, Vidailhet, Marie, Walker, Robert, van de Warrenburg, Bart, Wickremaratchi, Mirdhu, Williams, Nigel, Williams-Gray, Caroline H, Winder-Rhodes, Sophie, Stefánsson, Kári, Hardy, John, Heutink, Peter, Brice, Alexis, Gasser, Thomas, Singleton, Andrew B, Wood, Nicholas W, Chinnery, Patrick F, Arepalli, Sampath, Cookson, Mark R, Dillman, Allissa, Ferrucci, Luigi, Gibbs, J Raphael, Hernandez, Dena G, Johnson, Robert, Longo, Dan L, Majounie, Elisa, Nalls, Michael A, O’Brien, Richard, Singleton, Andrew B, Traynor, Bryan J, Troncoso, Juan, van der Brug, Marcel, Zielke, H Ronald, Zonderman, Alan B
Publicado em 2014