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Control of creatine metabolism by HIF is an endogenous mechanism of barrier regulation in colitis
Mucosal surfaces of the lower gastrointestinal tract are subject to frequent, pronounced fluctuations in oxygen tension, particularly during inflammation. Adaptive responses to hypoxia are orchestrated largely by the hypoxia-inducible transcription factors (HIFs). As HIF-1α and HIF-2α are coexpresse...
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| Asıl Yazarlar: | , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3856803/ https://ncbi.nlm.nih.gov/pubmed/24248342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302840110 |
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