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Central role for endothelial human deneddylase-1/SENP8 in fine-tuning the vascular inflammatory response
A deeper understanding of the mechanisms that control responses to inflammation is critical to the development of effective therapies. We sought to define the most proximal regulators of the Cullin-Ring-Ligases (CRL), which play a central role in the stabilization of NF-κB and HIF. In these studies,...
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Principais autores: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529810/ https://ncbi.nlm.nih.gov/pubmed/23209320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202041 |
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