Stabilization of HIF through inhibition of Cullin-2 neddylation is protective in mucosal inflammatory responses

There is interest in understanding post-translational modifications of proteins in inflammatory disease. Neddylation is the conjugation of the molecule neural precursor cell expressed, developmentally down-regulated 8 (NEDD8) to promote protein stabilization. Cullins are a family of NEDD8 targets im...

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Bibliographische Detailangaben
Veröffentlicht in:FASEB J
Hauptverfasser: Curtis, Valerie F., Ehrentraut, Stefan F., Campbell, Eric L., Glover, Louise E., Bayless, Amanda, Kelly, Caleb J., Kominsky, Douglas J., Colgan, Sean P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2015
Schlagworte:
Research Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285538/
https://ncbi.nlm.nih.gov/pubmed/25326537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-259663
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