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HIF-dependent regulation of claudin-1 is central to intestinal epithelial tight junction integrity
Intestinal epithelial cells (IECs) are exposed to profound fluctuations in oxygen tension and have evolved adaptive transcriptional responses to a low-oxygen environment. These adaptations are mediated primarily through the hypoxia-inducible factor (HIF) complex. Given the central role of the IEC in...
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| Published in: | Mol Biol Cell |
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| Main Authors: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The American Society for Cell Biology
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4462943/ https://ncbi.nlm.nih.gov/pubmed/25904334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-07-1194 |
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