Intestinal Epithelial Ecto-5′-Nucleotidase (CD73) Regulates Intestinal Colonization and Infection by Nontyphoidal Salmonella

Ecto-5′-nucleotidase (CD73) is expressed abundantly on the apical surface of intestinal epithelial cells (IECs) and functions as the terminal enzyme in the generation of extracellular adenosine. Previous work demonstrated that adenosine signaling in IECs results in a number of tissue-protective effe...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Kao, Daniel J., Saeedi, Bejan J., Kitzenberg, David, Burney, Krista M., Dobrinskikh, Evgenia, Battista, Kayla D., Vázquez-Torres, Andrés, Colgan, Sean P., Kominsky, Douglas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607412/
https://ncbi.nlm.nih.gov/pubmed/28717030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01022-16
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