Intestinal Epithelial Ecto-5′-Nucleotidase (CD73) Regulates Intestinal Colonization and Infection by Nontyphoidal Salmonella

Ecto-5′-nucleotidase (CD73) is expressed abundantly on the apical surface of intestinal epithelial cells (IECs) and functions as the terminal enzyme in the generation of extracellular adenosine. Previous work demonstrated that adenosine signaling in IECs results in a number of tissue-protective effe...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Kao, Daniel J., Saeedi, Bejan J., Kitzenberg, David, Burney, Krista M., Dobrinskikh, Evgenia, Battista, Kayla D., Vázquez-Torres, Andrés, Colgan, Sean P., Kominsky, Douglas J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
Sujets:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607412/
https://ncbi.nlm.nih.gov/pubmed/28717030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01022-16
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