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Crucial Role for Ecto-5′-Nucleotidase (CD73) in Vascular Leakage during Hypoxia

Extracellular adenosine has been widely implicated in adaptive responses to hypoxia. The generation of extracellular adenosine involves phosphohydrolysis of adenine nucleotide intermediates, and is regulated by the terminal enzymatic step catalyzed by ecto-5′-nucleotidase (CD73). Guided by previous...

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Detalhes bibliográficos
Main Authors: Thompson, Linda F., Eltzschig, Holger K., Ibla, Juan C., Van De Wiele, C. Justin, Resta, Regina, Morote-Garcia, Julio C., Colgan, Sean P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237012/
https://ncbi.nlm.nih.gov/pubmed/15583013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040915
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