Fluorescent Probes for Ecto-5′-nucleotidase (CD73)

[Image: see text] Ecto-5′-nucleotidase (CD73) catalyzes the hydrolysis of AMP to anti-inflammatory, immunosuppressive adenosine. It is expressed on vascular endothelial, epithelial, and also numerous cancer cells where it strongly contributes to an immunosuppressive microenvironment. In the present...

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Gepubliceerd in:ACS Med Chem Lett
Hoofdauteurs: Schmies, Constanze C., Rolshoven, Georg, Idris, Riham M., Losenkova, Karolina, Renn, Christian, Schäkel, Laura, Al-Hroub, Haneen, Wang, Yulu, Garofano, Francesca, Schmidt-Wolf, Ingo G. H., Zimmermann, Herbert, Yegutkin, Gennady G., Müller, Christa E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2020
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7667873/
https://ncbi.nlm.nih.gov/pubmed/33214837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00391
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