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Ecto-5’-nucleotidase, CD73, is an endothelium-derived hyperpolarizing factor synthase

OBJECTIVE: Adenosine dilates human coronary arteries by activating potassium channels in an endothelial cell-independent manner. Cell surface ecto-5’-nucleotidase (CD73) rapidly dephosphorylates extracellular adenosine 5’-monophosphate to adenosine. We tested the hypothesis that coronary vasodilatio...

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Detalhes bibliográficos
Main Authors: Ohta, Masanori, Toyama, Kazuyoshi, Gutterman, David D., Campbell, William B., Lemaître, Vincent, Teraoka, Ryutaro, Miura, Hiroto
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587694/
https://ncbi.nlm.nih.gov/pubmed/23288168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300600
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