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Hydrogen Peroxide Inhibits Cytochrome P450 Epoxygenases: Interaction Between Two Endothelium-Derived Hyperpolarizing Factors

The cytochrome P450 epoxygenase (CYP)-derived metabolites of arachidonic acid the epoxyeicosatrienoic acids (EETs) and hydrogen peroxide (H(2)O(2)) both function as endothelium-derived hyperpolarizing factors (EDHFs) in the human coronary microcirculation. However, the relative importance of and pot...

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Autors principals: Larsen, Brandon T., Gutterman, David D., Sato, Atsushi, Toyama, Kazuyoshi, Campbell, William B., Zeldin, Darryl C., Manthati, Vijay L., Falck, John R., Miura, Hiroto
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364729/
https://ncbi.nlm.nih.gov/pubmed/17975109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.159129
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