Gene Delivery of Cytochrome P450 Epoxygenase Ameliorates Monocrotaline-Induced Pulmonary Artery Hypertension in Rats

Pulmonary arterial hypertension (PAH) is a life-threatening disease that leads to progressive pulmonary hypertension, right heart failure, and death. Endothelial dysfunction and inflammation were implicated in the pathogenesis of PAH. Epoxyeicosatrienoic acids (EETs), products of the cytochrome P450...

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Autors principals: Zheng, Changlong, Wang, Luyun, Li, Rui, Ma, Ben, Tu, Ling, Xu, Xizhen, Dackor, Ryan T., Zeldin, Darryl C., Wang, Dao Wen
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2010
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993093/
https://ncbi.nlm.nih.gov/pubmed/20118222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0161OC
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